| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD107a (LAMP-1) |
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| Clone | 1D4B |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | Alexa Fluor? 647 conjugate |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor? 647 anti-mouse CD107a (LAMP-1). CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity. |
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| Immunogen | This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1. |
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| Other Names | Lysosome-Associated Membrane Protein 1, LAMP1, LGP-120 |
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| Gene, Accession # | Gene ID: 16783 |
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| Catalog # | 121609 |
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| Price | |
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| Order / More Info | CD107a (LAMP-1) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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