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產(chǎn)品名稱

CD107a (LAMP-1) Antibody from BIOLEGEND

產(chǎn)品貨號

121610

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CD107a (LAMP-1)
Clone	1D4B
Host Species	Rat
Reactive Species	mouse
Isotype	IgG2a, κ
Format	Alexa Fluor? 647 conjugate
Size	100 μg
Concentration	n/a
Applications	Flow Cytometry (FC), Immunofluorescence Microscopy (IF), IHC
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Alexa Fluor? 647 anti-mouse CD107a (LAMP-1). CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Immunogen	This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1.
Other Names	Lysosome-Associated Membrane Protein 1, LAMP1, LGP-120
Gene, Accession #	Gene ID: 16783
Catalog #	121610
Price
Order / More Info	CD107a (LAMP-1) Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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