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產(chǎn)品名稱

DMRT1 Antibody from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-C502226

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	DMRT1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	mouse, human
Isotype	n/a
Format	Protein G purified
Size	n/a
Concentration	n/a
Applications	ELISA, IHC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	DMRT1 Antibody LS-C502226. Specificity: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).
Immunogen	Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
Other Names	DMRT1, DMT1
Gene, Accession #	DMRT1, Gene ID: 1761
Catalog #	LS-C502226
Price
Order / More Info	DMRT1 Antibody from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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