| 產(chǎn)品詳情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | 236A/E7 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate, rhesus monkey |
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| Isotype | IgG1, kappa |
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| Format | biotin conjugate |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 μg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (236A/E7), Biotin, eBioscience?. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropa |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 50943, 574303; Uniprot: Q9BZS1 |
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| Catalog # | 13-4777-82 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18453600, 18684941, 19800266, 20617900, 20889558, 22131334, 23894725, 24978137, 25038256, 26482032, 26769139, 26999600, 27056325, 27246196, 27473163, 27708986, 28290464, 28388539, 28389592, 29166588, 29371976, 29416729 |
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