| 產(chǎn)品詳情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | FJK-16s |
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| Host Species | Rat |
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| Reactive Species | bovine, canine, feline, mouse, porcine, rat |
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| Isotype | IgG2a, kappa |
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| Format | eFluor 450 conjugate |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.06 μg/test |
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| Reviews / Ratings | |
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| Description | FOXP3 Monoclonal Antibody (FJK-16s), eFluor 450, eBioscience?. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, ente |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 100037405, 20371, 317382, 444998, 491876, 506053; Uniprot: Q99JB6 |
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| Catalog # | 48-5773-80 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19561540, 20205946, 20508851, 20701981, 20827278, 20956339, 21487509, 21541329, 21559526, 21677778, 21964024, 22045567, 22373353, 22450809, 22685592, 22701612, 22891339, 22952774, 22981537, 23046563, 23153292, 23180724, 23334789, 23432371, 23454771, 23644504, 23675534, 23756229, 23872063, 23893082, 24228231, 24253609, 24324812, 24359574, 24416033, 24452263, 24549276, 24646939, 24905997, 24935925, 25471571, 25642770, 25743066, 25917102, 25992288, 26041698, 26157038, 26208901, 26254339, 26284939, 26307665, 26325217, 26370586, 26416167, 26431376, 26509876, 26647186, 26693713, 26735971, 26832402, 26883594, 26994219, 27014269, 27031239, 27035332, 27040771, 27077371, 27160390, 27239480, 27245356, 27315465, 27498556, 27499704, 27565342, 27570837, 27618231, 27653816, 27699213, 27775547, 27863545, 27992401, 28011639, 28067667, 28134623, 28165507, 28197366, 28213589, 28235052, 28290453, 28303891, 28345650, 28368383, 28411140, 28454398, 28494937, 28504276, 28615031, 28696253, 28874832, 28944907, 29136509, 29180759, 29352742, 29386580, 29399067, 29410520, 29434788 |
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