| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | FOXP3 |
| Clone | FJK-16s |
| Host Species | Rat |
| Reactive Species | bovine, canine, feline, mouse, porcine, rat |
| Isotype | IgG2a, kappa |
| Format | eFluor 570 conjugate |
| Size | 25 μg |
| Concentration | n/a |
| Applications | Immunocytochemistry: 5 μg/mL, Immunofluorescence: 5 μg/mL, Immunohistochemistry (Frozen): 5 μg/mL, Immunohistochemistry (Paraffin): 5 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FOXP3 Monoclonal Antibody (FJK-16s), eFluor 570, eBioscience?. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, ente |
| Immunogen | n/a |
| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
| Gene, Accession # | Entrez: 100037405, 20371, 317382, 444998, 491876, 506053; Uniprot: Q99JB6 |
| Catalog # | 41-5773-80 |
| Price | |
| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | PubMed: 19924293, 20205946, 20508851, 20956339, 22685592, 23153292, 23432371, 23675534, 23872063, 24228231, 24359574, 24681564, 25642770, 25992288, 26157038, 26994219, 27031239, 27160390, 27457419, 27618231, 27699213, 29180759, 29352742, 29371976 |
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