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產(chǎn)品名稱

CENTG1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

PA5-24429

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

400 μL

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CENTG1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse
Isotype	n/a
Format	purified
Size	400 μL
Concentration	n/a
Applications	Western Blot: 1:1000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	CENTG1 Polyclonal Antibody. GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer
Immunogen	n/a
Other Names	CENTG1, GGAP2, PIKE, Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2, GTP-binding and GTPase activating protein 2, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, centaurin, gamma 1, cnt-g1, phosphatidylinositol-3-kinase enhancer, phosphoinosi
Gene, Accession #	Entrez: 116986, 216439; Uniprot: Q3UHD9, Q99490
Catalog #	PA5-24429
Price
Order / More Info	CENTG1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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