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產(chǎn)品名稱

DOK1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

PA5-32384

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

500 μL

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	DOK1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	purified
Size	500 μL
Concentration	n/a
Applications	Immunohistochemistry (Paraffin): 1:50
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	DOK1 Polyclonal Antibody. DOK-1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK-1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK-1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK-1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
Immunogen	n/a
Other Names	P62DOK, Downstream of tyrosine kinase 1, docking protein 1, docking protein 1 downstream of tyrosine kinase 1, p62dok, pp62
Gene, Accession #	Entrez: 1796; Uniprot: Q99704
Catalog #	PA5-32384
Price
Order / More Info	DOK1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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