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        產(chǎn)品名稱(chēng) PAK2 Antibody from INVITROGEN ANTIBODIES
        產(chǎn)品貨號(hào) A301-264A-T
        產(chǎn)品價(jià)格 現(xiàn)貨詢(xún)價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 20 μL
        產(chǎn)品品牌 INVITROGEN ANTIBODIES
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityPAK2
        Clonepolyclonal
        Host SpeciesRabbit
        Reactive Specieshuman
        Isotypen/a
        Formatpurified
        Size20 μL
        Concentrationn/a
        ApplicationsWestern Blot: 1:1,000
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionPAK2 Polyclonal Antibody. Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek do
        Immunogenn/a
        Other NamesPAK65, PAKgamma
        Gene, Accession #Entrez: 5062; Uniprot: Q13177
        Catalog #A301-264A-T
        Price
        Order / More InfoPAK2 Antibody from INVITROGEN ANTIBODIES
        Product Specific Referencesn/a
        產(chǎn)品資料
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