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產(chǎn)品名稱

PAK2 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

A301-263A

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μL

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	PAK2
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse
Isotype	n/a
Format	purified
Size	100 μL
Concentration	n/a
Applications	Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	PAK2 Polyclonal Antibody. Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek do
Immunogen	n/a
Other Names	PAK65, PAKgamma
Gene, Accession #	Entrez: 224105, 5062; Uniprot: Q13177, Q8CIN4
Catalog #	A301-263A
Price
Order / More Info	PAK2 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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