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        產品名稱 PAK1/PAK2 Antibody from INVITROGEN ANTIBODIES
        產品貨號 PA5-36918
        產品價格 現貨詢價,電話:010-67529703
        產品規(guī)格 100 μl
        產品品牌 INVITROGEN ANTIBODIES
        產品概述
        產品詳情
        Edit&nbsp
        Antigenic SpecificityPAK1/PAK2
        Clonepolyclonal
        Host SpeciesRabbit
        Reactive Specieshuman, mouse, rat
        Isotypen/a
        Formatpurified
        Size100 μl
        Concentrationn/a
        ApplicationsImmunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionPAK1/PAK2 Polyclonal Antibody. Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to se
        Immunogenn/a
        Other NamesSerine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK1, PAK alpha, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK-2p27, PAK-2p34, C-t-PAK2, PAK2, PAK gamma
        Gene, Accession #Entrez: 18479, 224105, 29431, 29432, 5058, 5062; Uniprot: O88643, P35465, Q13153, Q13177, Q64303, Q8CIN4
        Catalog #PA5-36918
        Price
        Order / More InfoPAK1/PAK2 Antibody from INVITROGEN ANTIBODIES
        Product Specific Referencesn/a
        產品資料
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