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                產(chǎn)品名稱
                YES1 / c-Yes Antibody from LIFESPAN BIOSCIENCES INC.
            
        
            
        
                產(chǎn)品貨號
                LS-C500041
            
        
            
        
                產(chǎn)品價(jià)格
                現(xiàn)貨詢價(jià)，電話：010-67529703
                
            
        
            
        
                產(chǎn)品規(guī)格
                n/a
            
        
            
        
                產(chǎn)品品牌
                LIFESPAN BIOSCIENCES INC.
            
        
            
        
                產(chǎn)品概述
                
            
        
            
        
                產(chǎn)品詳情
                  
                
        
                  
                    
                    
        Edit&nbsp
        
                    
                    
                     
        Antigenic SpecificityYES1 / c-Yes
        
                    
                     
        Clonepolyclonal
        
                    
                     
        Host SpeciesRabbit
        
                    
                     
        Reactive Specieshuman
        
                    
                     
        Isotypen/a
        
                    
                     
        Formatperoxidase (HRP) conjugate
        
                    
                     
        Sizen/a
        
                    
                     
        Concentrationn/a
        
                    
                     
        ApplicationsELISA
        
                    
                     
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        
                    
                     
        DescriptionYES1 / c-Yes Antibody (HRP) LS-C500041. Specificity: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
        
                    
                     
        ImmunogenRecombinant human Tyrosine-protein kinase Yes protein (1-155AA)
        
                    
                     
        Other NamesYES1, C-yes, Cyes, Cellular yes-1 protein, HsT441, Oncogene kinase yes1, p61-YES, p61yes, p62c-yes, Proto-oncogene c-Yes, Tyrosine-protein kinase Yes, Yes kinase, v-yes, Yes, Yamaguchi sarcoma oncogene
        
                    
                     
        Gene, Accession #YES1, Gene ID: 7525
        
                    
                     
        Catalog #LS-C500041
        
                    
                     
        Price
        
                    
                     
        Order / More InfoYES1 / c-Yes Antibody from LIFESPAN BIOSCIENCES INC.
        
                    
                     
        Product Specific Referencesn/a
        
                    
                          
                
            
            
        
                產(chǎn)品資料
                
            
        
        
        
    









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