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產(chǎn)品名稱

TRAF6 Antibody from ABBEXA

產(chǎn)品貨號

abx000926

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 μl, 100 μl, 200 μl

產(chǎn)品品牌

ABBEXA

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	TRAF6
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat
Isotype	n/a
Format	affinity purified
Size	50 μl, 100 μl, 200 μl
Concentration	> 1 mg/ml
Applications	WB, IF/ICC. RUO
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	TRAF6 Antibody is a Rabbit Polyclonal antibody against TRAF6. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.
Immunogen	Recombinant protein of human TRAF6.
Other Names	RNF85; TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; TNF Receptor Associated Factor 6; TRAF6; TRAF 6; TRAF-6; MGC:3310
Gene, Accession #	TRAF6, Gene ID: 7189, SwissProt: Q9Y4K3
Catalog #	abx000926
Price
Order / More Info	TRAF6 Antibody from ABBEXA
Product Specific References	n/a
產(chǎn)品資料

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