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產(chǎn)品名稱

UBE2V1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號

PA1-41381

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	UBE2V1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	purified
Size	100 μg
Concentration	n/a
Applications	Western Blot: 1-3 μg/mL
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	UBE2V1 Polyclonal Antibody. The E2 enzyme, Ubc13, and the E2 enzyme variants, Uevs, form stable, high affinity complexes for the assembly of Lys63-linked ubiquitin chains. This complex has been shown to activate NF-kB signaling pathway by linking TRAF6 to IKKs. Blockade of this polyubiquitin chain synthesis, but not inhibition of the proteasome, prevents the activation of IKK by TRAF6. These results suggest a new regulatory function for ubiquitin, in which IKK is activated through the assembly of Lys63-linked polyubiquitin chains. The UEV proteins are also involved in the control of differentiation.
Immunogen	n/a
Other Names	CROC1, TRAF6-regulated IKK activator 1 beta, Uev1A, CROC-1UBE2V, ubiquitin-conjugating enzyme E2 variant 1, UEV1A, UEV-1CIR1, UEV1DNA-binding protein
Gene, Accession #	Entrez: 7335; Uniprot: Q13404
Catalog #	PA1-41381
Price
Order / More Info	UBE2V1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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