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產品名稱

RIP1 Antibody from INVITROGEN ANTIBODIES

產品貨號

MA5-26426

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

100 μl

產品品牌

INVITROGEN ANTIBODIES

產品概述

產品詳情

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Antigenic Specificity	RIP1
Clone	OTI2D6
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	purified
Size	100 μl
Concentration	n/a
Applications	Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	RIP1 Monoclonal Antibody (OTI2D6). Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes e
Immunogen	n/a
Other Names	OTTHUMP00000015955; RIP-1; cell death protein RIP; receptor interacting protein; receptor-interacting protein 1; receptor-interacting serine/threonine-protein kinase 1; serine/threonine-protein kinase RIP
Gene, Accession #	Entrez: 8737; Uniprot: Q13546
Catalog #	MA5-26426
Price
Order / More Info	RIP1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產品資料

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