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產品名稱

ASK1 Antibody from INVITROGEN ANTIBODIES

產品貨號

MA5-15861

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

100 μL

產品品牌

INVITROGEN ANTIBODIES

產品概述

產品詳情

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Antigenic Specificity	ASK1
Clone	2E4
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	purified
Size	100 μL
Concentration	n/a
Applications	Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	ASK1 Monoclonal Antibody (2E4). Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. A
Immunogen	n/a
Other Names	RP3-325F22.4, ASK1, MAPKKK5, MEKK5, ASK-1; MAP/ERK kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1
Gene, Accession #	Entrez: 4217; Uniprot: Q99683
Catalog #	MA5-15861
Price
Order / More Info	ASK1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	PubMed: 27364558
產品資料

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