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產(chǎn)品名稱

ASK1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

PA1-12518

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	ASK1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	purified
Size	100 μg
Concentration	n/a
Applications	Western Blot: Assay Dependent
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	ASK1 Polyclonal Antibody. Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is
Immunogen	n/a
Other Names	MAPKKK5, MEKK5, MAP3K5
Gene, Accession #	Entrez: 4217; Uniprot: Q99683
Catalog #	PA1-12518
Price
Order / More Info	ASK1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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