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產(chǎn)品名稱

ASK1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號

PA5-28692

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μL

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ASK1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse
Isotype	n/a
Format	purified
Size	100 μL
Concentration	n/a
Applications	Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	ASK1 Polyclonal Antibody. Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is
Immunogen	n/a
Other Names	ASK1, MAPKKK5, MEKK5, ASK-1, MAP/ERK kinase kinase 5, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, apoptosis signal regulating kinase 1, apoptosis signal-regulating kinase 1
Gene, Accession #	Entrez: 26408, 4217; Uniprot: O35099, Q99683
Catalog #	PA5-28692
Price
Order / More Info	ASK1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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