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產(chǎn)品名稱

ATXN3 Antibody from SICGEN ANTIBODIES

產(chǎn)品貨號(hào)

AB10089-200

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

600 μg

產(chǎn)品品牌

SICGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ATXN3
Clone	polyclonal
Host Species	Goat
Reactive Species	human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotype	n/a
Format	immunoaffinity purified
Size	600 μg
Concentration	3 mg/ml
Applications	WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder. Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot.
Immunogen	Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Other Names	AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein
Gene, Accession #	ATXN3, Gene ID: 4287
Catalog #	AB10089-200
Price
Order / More Info	ATXN3 Antibody from SICGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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