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產(chǎn)品名稱(chēng)

Estrogen Receptor 1 (ESR1) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN1514054

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

200 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Estrogen Receptor 1 (ESR1)
Clone	polyclonal
Host Species	Rabbit
Reactive Species	mouse, rat, human
Isotype	n/a
Format	affinity purified
Size	200 μg
Concentration	n/a
Applications	Western Blotting (WB)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Estrogen receptor alpha (ERalpha), a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ERalpha regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ERalpha activity. ERalpha is phosphorylated on multiple sites. Ser104, 106, 118 and 167 are located in the amino-terminal transcription activation function domain AF-1, and phosphorylation of these serines plays an important role in regulating ERalpha activity. Ser118 may be the substrate of the transcription regulatory kinase CDK7. Ser167 may be phosphorylated by p90RSK and Akt. Phosphorylation of Ser167 may confer tamoxifen resistance in breast cancer patients.Synonyms: ESR1, DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1 , Estrogen Receptor alpha
Immunogen	Recombinant protein of human ESR1
Other Names	ACTGP1\|ACT1GP1\|HY-psi-gamma-AC6\|ER[b]2\|ER[b]a\|zfER[b]2\|zfER-beta2\|XER\|era\|esr\|esra\|nr3a1\|ERbeta\|xesr-1\|ERalpha\|xlERalpha1\|xlERalpha2\|LOC398733\|LOC398734\|2610524P08Rik\|9130407C09Rik\|AU019798\|Era\|M-ERA\|MERA-S\|MERA-W\|ERA\|ERAL1A\|H-ERA\|HERA-A\|HERA-B\|er\|esr1\|ER\|ESR\|ESRA\|ESTRR\|NR3A1\|ER-alpha\|Esr\|RNESTROR\|ERALPHA\|ER[a]\|eralpha\|zfER[a]\|ESR1\|AA420328\|AU041214\|ERa\|Estr\|Estra\|Nr3a1
Gene, Accession #	Gene ID: 2099,13982,24890
Catalog #	ABIN1514054
Price
Order / More Info	Estrogen Receptor 1 (ESR1) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

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