| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | Noggin, human recombinant |
| Description | Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant human N |
| Size | 100 μg |
| Concentration | n/a |
| Applications | RUO |
| Other Names | NOG |
| Gene, Accession, CAS # | NOG, Gene ID: 9241, Accession: Q13253 |
| Catalog # | 4675-100 |
| Price | |
| Order / More Info | Noggin, human recombinant from BIOVISION, INC. |
| Product Specific References | n/a |
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