| 產(chǎn)品詳情 |
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| Antigenic Specificity | CCR5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 μl, 400 μl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. This CCR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the Central region of human CCR5. |
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| Immunogen | Human CCR5. |
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| Other Names | C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; Ccr5; Cmkbr5; MIP-1 alpha receptor; CD195; C-C chemokine receptor type 5C-C CKR-5CC-CKR-5CCR-5CCR5; CHEMR13; HIV-1 fusion coreceptor; CD195 antigen; CKR5; HIV-1 fusion co-receptor; CCCKR5; CKR-5; FLJ78003; IDDM22; Chemokine (C-C motif) receptor 5; Chemokine C-C-Motif Receptor 5; CC-CKR5; Protein name C-C chemokine receptor type 5; Synonyms C-C CKR-5 |
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| Gene, Accession # | SwissProt: P51681 |
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| Catalog # | abx031116 |
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| Price | |
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| Order / More Info | CCR5 Antibody from ABBEXA |
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| Product Specific References | n/a |
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