| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD80 |
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| Clone | 2D10 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: rhesus |
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| Isotype | IgG1, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-human CD80. CD80,?also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. |
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| Immunogen | n/a |
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| Other Names | B7-1, B7, BB1 |
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| Gene, Accession # | Gene ID: 941 |
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| Catalog # | 305219 |
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| Price | |
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| Order / More Info | CD80 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 18316378,22312112,23936476,25295996,25348634 |
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