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產(chǎn)品名稱

QIP1 / KPNA4 Antibody from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-C499200

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	QIP1 / KPNA4
Clone	polyclonal
Host Species	Rabbit
Reactive Species	mouse, human
Isotype	n/a
Format	Protein G purified
Size	n/a
Concentration	n/a
Applications	ELISA, IF, IHC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	QIP1 / KPNA4 Antibody LS-C499200. Specificity: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
Immunogen	Recombinant Human Importin subunit alpha-3 protein (51-239AA)
Other Names	KPNA4, Importin subunit alpha-4, Importin alpha Q1, Karyopherin subunit alpha-4, SRP3, IPOA3, QIP1
Gene, Accession #	KPNA4, Gene ID: 3840
Catalog #	LS-C499200
Price
Order / More Info	QIP1 / KPNA4 Antibody from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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