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| Product Name | Presenilin 1 (PSEN1) peptide |
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| Description | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | pre1|psen|zfPS1|zf-PS1|ad3|fad|ps1|s182|X-PS-beta|X-PS-alpha|AD3|FAD|PS-1|PS1|S182|Ad3h |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN937808 |
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| Price | |
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| Order / More Info | Presenilin 1 (PSEN1) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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