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        產(chǎn)品名稱 PICK1 Antibody from BIOLEGEND
        產(chǎn)品貨號 830904
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 100 μg
        產(chǎn)品品牌 BIOLEGEND
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityPICK1
        CloneL20/8
        Host SpeciesMouse
        Reactive Specieshuman, mouse, rat
        IsotypeIgG2a
        Formatperoxidase (HRP) conjugate
        Size100 μg
        Concentrationn/a
        ApplicationsWestern Blot (WB)
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionHRP anti-PICK1. Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function. (Uniprot)
        ImmunogenThis monoclonal antibody was raised against a fusion protein corresponding to amino acids 10-130 of rat PICK1 protein.
        Other NamesPRKCA-binding protein, protein interacting with C kinase 1, protein kinase C-alpha-binding protein, protein that interacts with C kinase 1, protein kinase C, alpha binding protein, PRKCABP, MMS-5179-100
        Gene, Accession #Gene ID: 84591
        Catalog #830904
        Price
        Order / More InfoPICK1 Antibody from BIOLEGEND
        Product Specific Referencesn/a
        產(chǎn)品資料
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