| 產(chǎn)品詳情 |
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| Antigenic Specificity | TRIP10/CIP4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRIP10/CIP4 Polyclonal Antibody. Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention |
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| Immunogen | n/a |
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| Other Names | Cdc42-interacting protein 4, Protein Felic, Salt tolerant protein, hSTP, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10, TRIP10, CIP4, STOT, STP |
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| Gene, Accession # | Entrez: 106628, 9322; Uniprot: Q15642, Q8CJ53 |
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| Catalog # | A301-186A |
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| Price | |
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| Order / More Info | TRIP10/CIP4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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