| 產(chǎn)品詳情 |
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| Antigenic Specificity | P Glycoprotein/ABCB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100ug |
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| Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband? antibody for P Glycoprotein detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. |
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| Immunogen | A synthetic peptide corresponding to a sequence of human P Glycoprotein (QAQDRKLSTKEALDESIPPVSFWRIMKLNLTEWPY). |
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| Other Names | Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD243; ABCB1; MDR1; PGY1 |
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| Gene, Accession # | ABCB1, UniProt: P08183 |
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| Catalog # | A00049-1 |
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| Price | |
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| Order / More Info | P Glycoprotein/ABCB1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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