91色在线,黄动漫免费看,欧美第一黄色,抽插.com,自拍偷拍性爱,天天操中文网,精品免费囯产一区二区三区四区视频,四虎影院大香蕉视频

<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

Sortilin 1 (SORT1) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN1842052

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	Sortilin 1 (SORT1) (C-Term)
Clone	polyclonal
Host Species	Rabbit
Reactive Species	rat, mouse
Isotype	n/a
Format	unconjugated
Size	500 μg
Concentration	n/a
Applications	Immunohistochemistry (IHC),Western Blotting (WB)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	FUNCTION: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi. SUBUNIT: Interacts with the cytosolic adapter proteins GGA1 and GGA2. Interacts with numerous ligands including the receptor-associated protein LRPAP1/RAP and GM2A, LPL, PSAP and SLC2A4. Forms a complex with NGFR which binds specifically to the precursor form of NGFB (proNGFB). Interacts with the precursor form of BDNF (proBDNF). SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein. Note: Localized to membranes of the endosomes, Golgi stack, lysosomes and nucleus. Localization to the plasma membrane in adipocytes is enhanced by insulin. Localized to the endoplasmic reticulum and the plasma membrane. Also found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. TISSUE SPECIFICITY: Highly expressed in fat, brain, and lung. Expressed in neuronal bodies and dendrites of the piriform cortex and hippocampus. Also expressed in the islands of Calleja, medial and lateral septal nuclei, amygdaloid nuclei, thalamic nuclei, the supraoptic nucleus, the substantia nigra, the Purkinje layer of the cerebellar cortex and the cranial motor nerve nuclei of the brainstem.Synonyms: Neurotensin receptor 3, NTR3, Glycoprotein 110, Gp110, Nt3, Nts3
Immunogen	A synthetic peptide from the extracellular, c-terminal region of rat Sortilin (Neurotensin receptor 3, NTR3, Sort1) conjugated to immunogenic carrier protein was used as the antigen.
Other Names	SORT1\|19.m02079\|gp95\|ldlcq6\|sortilin\|Gp95\|LDLCQ6\|NT3\|2900053A11Rik\|AI852375\|Ntr3\|Ntsr3\|Nt3\|Nts3\|sort1\|zgc:85953
Gene, Accession #	Gene ID: 20661,83576
Catalog #	ABIN1842052
Price
Order / More Info	Sortilin 1 (SORT1) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>