| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | Sortilin 1 (SORT1) (N-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | unconjugated |
|---|
| Size | 500 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Function: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.Subunit: Interacts with the cytosolic adapter proteins GGA1 and GGA2. Interacts with numerous ligands including the receptor-associated protein LRPAP1/RAP and GM2A, LPL, PSAP and SLC2A4. Forms a complex with NGFR which binds specifically to the precursor form of NGFB (proNGFB). Interacts with the precursor form of BDNF (proBDNF).Subcellular location: Membrane, Single-pass type I membrane protein. Note: Localized to membranes of the endosomes, Golgi stack, lysosomes and nucleus. Localization to the plasma membrane in adipocytes is enhanced by insulin. Localized to the endoplasmic reticulum and the plasma membrane. Also found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes.Tissue specificity: Expressed at high levels in brain, spinal cord, heart, skeletal muscle, thyroid, placenta and testis. Expressed at lower levels in lymphoid organs, kidney, colon and liver. Also known as: Neurotensin receptor 3, NTR3, NT3, Glycoprotein 95, Gp95, 100 kDa NT receptor. |
|---|
| Immunogen | A synthetic peptide from the extracellular, N-terminal region of human Sortilin (Neurotensin receptor 3, NTR3, Sort1) conjugated to an immunogenic carrier protein was used as the antigen. |
|---|
| Other Names | SORT1|19.m02079|gp95|ldlcq6|sortilin|Gp95|LDLCQ6|NT3|2900053A11Rik|AI852375|Ntr3|Ntsr3|Nt3|Nts3|sort1|zgc:85953 |
|---|
| Gene, Accession # | Gene ID: 6272 |
|---|
| Catalog # | ABIN350872 |
|---|
| Price | |
|---|
| Order / More Info | Sortilin 1 (SORT1) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 16710414, 12209882, 12598608, 9756851, 10085125, 11331584, 11859376, 15930396, 18088087, 9013611 |
|---|
| 產(chǎn)品資料 |
|
色综合激情,手伸进老师湿润的三角裤,吃大鸡巴
|
爆操乱伦,黄色一级国产,首页123操逼
|
亚洲无码123,女攻男受开发菊h女尊产乳,疯狂操逼大香蕉
|
日韩国产,后宫妃h狠狠肉,高清无码在线免费观看
|
BBB操BBB,亚州成亚州二三四五区,97这里只有精品
|
只有精品,刑警娇妻穿着乳环被调教,插逼逼AV
|
亚洲天天搞,亚洲一区二区三区袜高跟,男人天堂2024在线
|
色88综合网,大香蕉色五月,黄片在线浏览
|
狠狠的操,chinese勾搭少妇videos,日本三级小视频
|
国产精品在线观看,操女人免费视频,大香蕉中文在线
|
|