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產(chǎn)品名稱

Acidic Sphingomyelinase Assay Kit (red fluorescence) from AAT BIOQUEST, INC.

產(chǎn)品貨號

13622

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

200 tests

產(chǎn)品品牌

AAT BIOQUEST, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Acidic Sphingomyelinase Assay Kit (red fluorescence)
Description	Amplite? Fluorimetric Acidic Sphingomyelinase Assay Kit Red Fluorescence. Sphingomyelinase (SMase) is an enzyme that is responsible for cleaving sphingomyelin (SM) to phosphocholine and ceramide. Activation of SMases plays an important role in the cellular response such as regulation of cell growth, cell differentiation, cell cycle arrest and programmed cell death. Five types of sphingomyelinase (SMase) have been identified based on their cation dependence and pH optima of action, including lysosomal acid SMase, secreted zinc-dependent acid SMase, magnesium-dependent neutral SMase, magnesium-independent neutral SMase and alkaline SMase. Among them, the lysosomal acidic SMase and the magnesium-dependent neutral SMase are considered to be the major factors for the production of ceramide in cellular stress responses. Our Amplite? Fluorimetric Acidic Sphingomyelinase Assay Kit provides one of the most sensitive methods for detecting acidic SMase activity or screening its inhibitors. The kit uses Amplite? Red as a fluorogenic probe to indirectly quantify the phosphocholine produced from the hydrolysis of sphingomyelin (SM) by sphingomyelinase (SMase). It can be used for measuring the SMase activity in blood, cell extracts or other solutions. The fluorescence intensity of Amplite? Red is proportional to the formation of phosphocholine, therefore to the SMase activity. The kit is an optimized mix and read assay compatible with HTS liquid handling instruments.
Size	200 tests
Concentration	n/a
Applications	Biossay, Fluorometric
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	13622
Price
Order / More Info	Acidic Sphingomyelinase Assay Kit (red fluorescence) from AAT BIOQUEST, INC.
Product Specific References	n/a
產(chǎn)品資料

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