| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD81 |
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| Clone | QV-6A8 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | flow cytometry, CELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry. |
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| Immunogen | cDNA |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | GM-1113 |
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| Price | |
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| Order / More Info | CD81 Antibody from ALDEVRON FREIBURG GmbH |
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| Product Specific References | n/a |
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