| 產(chǎn)品詳情 |
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| Antigenic Specificity | S100A4 |
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| Clone | NJ-4F3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | flow cytometry and immunohistochemistry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | S100 calcium binding protein A4 (S100A4) is a member of the S100 family of calcium-binding proteins that contain two Ca(2+)-binding sites including a canonical EF-hand motif. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. It is secreted by unknown mechanisms, thus, paracrinely stimulating a variety of cellular responses, including angiogenesis and neuronal growth. S100A4 has been shown to be a prognostic marker in a number of human cancers, including esophageal-squamous cancers, non-small lung cancers, primary gastric cancers, malignant melanomas, prostate cancers, bladder cancers, and pancreatic carcinomas. The universality of S100A4 expression in a variety of cancers illustrates the potential use of S100A4 as a marker for tumor metastasis and disease progression. |
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| Immunogen | cDNA |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | GM-0908 |
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| Price | |
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| Order / More Info | S100A4 Antibody from ALDEVRON FREIBURG GmbH |
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| Product Specific References | n/a |
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