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產(chǎn)品名稱

ABL2 Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN965499

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

0.1 mL

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ABL2
Clone	1H1
Host Species	Mouse
Reactive Species	human, mouse
Isotype	IgG1
Format	ascites
Size	0.1 mL
Concentration	n/a
Applications	Western Blotting (WB),Immunofluorescence (IF),ELISA
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.Synonyms: ARG, ABLL, FLJ22224, FLJ31718, FLJ41441
Immunogen	Purified recombinant fragment of ABL2 expressed in E. Coli.
Other Names	ABLL\|ARG\|Abll\|Arg\|AA536808
Gene, Accession #	Gene ID: 27,11352
Catalog #	ABIN965499
Price
Order / More Info	ABL2 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

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