| 產(chǎn)品詳情 |
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| Antigenic Specificity | AIFM1 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, ICC/IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Apoptosis-inducing factor 1, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. |
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| Immunogen | Recombinant human AIFM1 (98-609aa) purified from E. coli |
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| Other Names | Apoptosis-inducing factor 1 mitochondrial isoform 2 precursor, Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, AIF, CMTX4, COWCK, COXPD6, PDCD8 |
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| Gene, Accession # | NP 665811 |
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| Catalog # | ATGA0411 |
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| Price | |
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| Order / More Info | AIFM1 Antibody from ATGen |
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| Product Specific References | n/a |
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