| 產(chǎn)品詳情 |
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| Antigenic Specificity | AKT1/3 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, Flow cytometry, ICC/IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AKT1, also known as RAC-alpha serine/threonine-protein kinase, is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. |
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| Immunogen | Recombinant human AKT1 (1-480aa) purified from insect cell. |
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| Other Names | RAC-alpha serine/threonine-protein kinase, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA |
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| Gene, Accession # | NP 001014432 |
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| Catalog # | ATGA0480 |
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| Price | |
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| Order / More Info | AKT1/3 Antibody from ATGen |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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