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產(chǎn)品名稱

APP Antibody from ATGen

產(chǎn)品貨號(hào)

AAP0836

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100ul, 50ul

產(chǎn)品品牌

ATGen

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	APP
Clone	monoclonal
Host Species	Mouse
Reactive Species	human, mouse
Isotype	IgG2b, k
Format	purified
Size	100ul, 50ul
Concentration	n/a
Applications	ELISA, WB, Flow cytometry, ICC/IF
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Amyloid precursor protein (APP) is the precursor molecule whose proteolysis generates amyloid beta (AB), a 39- to 42- amino acid peptide and this amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's diseases patients. APP is an integral membrane protein that is phosphorylated in the cytoplasmic and extracellular domains. It has been reported that cell-surface APP plays a role in neurite extension of primary cultured hippocampal neurons. The large extracellular domain of APP is also reported to bind extracellular matrix molecules such as heparin, laminin, and collagen, which can mediate cell adhesion and neurite outgrowth. Abnormal regulation of the metabolism of APP may contribute to the deposition of plaques.
Immunogen	Recombinant human APP (18-289aa) purified from E. coli
Other Names	amyloid beta A4 protein precursor, isoform , amyloid beta (A4) precursor protein, Alzheimer disease, peptidase nexin-II
Gene, Accession #	NP 000475
Catalog #	AAP0836
Price
Order / More Info	APP Antibody from ATGen
Product Specific References	n/a
產(chǎn)品資料

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