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        產(chǎn)品名稱 CD14 Antibody from ATGen
        產(chǎn)品貨號 ATGA0339
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 100ul, 50ul
        產(chǎn)品品牌 ATGen
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityCD14
        Clonemonoclonal
        Host SpeciesMouse
        Reactive Specieshuman
        IsotypeIgG2b, k
        Formatpurified
        Size100ul, 50ul
        Concentrationn/a
        ApplicationsELISA, WB, Flow cytometry
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionThe protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48kDa) or is directly secreted from intracellular vesicles (56kDa).The x-ray crystal structure of human CD14 reveals a monomeric, bent solenoid structure containing a hydrophobic amino-terminal pocket. CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns such as lipoteichoic acid.
        ImmunogenRecombinant human CD14 (20-349aa) purified from E.coli.
        Other Namesmonocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
        Gene, Accession #NP 001167576
        Catalog #ATGA0339
        Price
        Order / More InfoCD14 Antibody from ATGen
        Product Specific Referencesn/a
        產(chǎn)品資料
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