| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD46 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, Flow cytometry, ICC/IF, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types. |
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| Immunogen | Recombinant human CD46 (35-313aa) purified from E. coli |
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| Other Names | Membrane cofactor protein isoform 14, AHuS2, MCP, MIC10, TLX, TRA2.10 |
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| Gene, Accession # | NP 758860 |
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| Catalog # | ATGA0326 |
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| Price | |
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| Order / More Info | CD46 Antibody from ATGen |
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| Product Specific References | n/a |
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