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產(chǎn)品名稱(chēng)

ADAR1 Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

685901

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

25 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	ADAR1
Clone	15.8.6
Host Species	Mouse
Reactive Species	human
Isotype	IgG
Format	purified
Size	25 μg
Concentration	n/a
Applications	Western Blot (WB), ICC, KO/KD-Western Blot (WB), IHC-P
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Purified anti-ADAR1. Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosine residues to inosine in double-stranded RNAs (dsRNAs). The translation machinery reads inosine as guanosine, leading to recoding of a relatively small number of neurotransmitter and ion channel genes and diversification of their functions. Three ADAR gene family members (ADAR1-3) are known in vertebrates. Members of the ADAR gene family share common structural features, such as the presence of multiple dsRNA binding domains (dsRBDs) and a separate deaminase domain. Three repeats of dsRBD are present in ADAR1, while only two repeats are found in ADAR2 and ADAR. ADAR1 increases the rate of pre-microRNA cleavage by Dicer and facilitates loading of miRNA onto RNA-induced silencing complexes. ADAR1 differentiates its functions in RNA editing and RNAi by formation of either ADAR1/ADAR1 homodimer or Dicer/ADAR1 heterodimer complexes. The deficiency of ADAR1 embryonically lethal due to overall apoptosis.
Immunogen	dsRNA binding domain
Other Names	DRADA, Double-stranded RNA-specific adenosine deaminase, p136, IFI-4
Gene, Accession #	Gene ID: 103
Catalog #	685901
Price
Order / More Info	ADAR1 Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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