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| Antigenic Specificity | AICD |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | ELISA, IHC, Western Blot (WB), Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-AICD. APP intracellular domain (AICD) is a peptide fragment that results from intramembraneous proteolysis of the amyloid precursor protein (APP). APP is a single-pass transmembrane protein that is involved in the pathophysiology of Alzheimer's disease (AD). APP is cleaved by gamma-secretase that releases the AICD into the cytoplasm. Soon after its release from the membrane, AICD is rapidly degraded in the cytoplasm partly by insulin degrading enzymes. |
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| Immunogen | n/a |
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| Other Names | Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, SIG-39148-050 |
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| Gene, Accession # | Gene ID: 351 |
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| Catalog # | 811901 |
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| Price | |
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| Order / More Info | AICD Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 22031884 |
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