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產(chǎn)品名稱

Aiolos Antibody from BIOLEGEND

產(chǎn)品貨號

653206

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Aiolos
Clone	8B2
Host Species	Mouse
Reactive Species	mouse
Isotype	IgG1, κ
Format	Alexa Fluor? 647 conjugate
Size	100 μg
Concentration	n/a
Applications	Intracellular Staining for Flow Cytometry (ICFC)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Alexa Fluor? 647 anti-mouse Aiolos. Aiolos, an Ikaros family member, is also known as Izkf3. It has a molecular weight of 58 kD and shows 70% homology to the Ikaros isoform, Ik-1, particularly in the DNA binding and C-terminal domains. Aiolos can form a heteromer with Ikaros or exist as a homodimer. The homomeric complex is a potent transcriptional activator.? Unlike Ikaros, Aiolos is expressed in late fetal thymus and adult lymphoid organs. Among the adult hematopoietic progenitors, Aiolos is expressed at low levels in mulitpotent but not in pluripotent stem cells. When these multipotent progenitors become more restricted to T and B lymphoid pathways there is an upregulation in Aiolos expression. The highest expression of Aiolos is detected in the spleen (especially in B-cells) followed by thymus and bone marrow, and cannot be detected in the non-lymphoid organs. Aiolos plays an important role in lymphocyte proliferation and differentiation.
Immunogen	N-terminal half of mouse Aiolos fused to GST
Other Names	Ikzf3, Zfpn1a3, Znfn1a3
Gene, Accession #	Gene ID: 22780
Catalog #	653206
Price
Order / More Info	Aiolos Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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