| 產(chǎn)品詳情 |
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| Antigenic Specificity | Alix |
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| Clone | 3A9 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, and frog |
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| Isotype | IgG1, κ |
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| Format | Alexa Fluor? 594 conjugate |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor? 594 anti-Alix. Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. The predicted molecular weight is approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. The Bro1 domain interacts with CHMP4b, which is also involved in endosomal sorting. |
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| Immunogen | Recombinant full-length human Alix protein |
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| Other Names | PDCD6IP, PDCD6 interacting protein, AIP1, Hp95 |
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| Gene, Accession # | Gene ID: 10015 |
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| Catalog # | 634504 |
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| Price | |
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| Order / More Info | Alix Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 23364798,25535287 |
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