| 產(chǎn)品詳情 |
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| Antigenic Specificity | Allergin-1 |
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| Clone | TX83 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse Allergin-1. Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule. |
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| Immunogen | Transfected cells expressing allergin-1-Flag |
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| Other Names | Allergy inhibitory receptor 1 (Allegrin1), Mast cell Ag-32 (MCA-32, MCA32), Milr1 |
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| Gene, Accession # | Gene ID: 380732 |
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| Catalog # | 141807 |
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| Price | |
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| Order / More Info | Allergin-1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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