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產(chǎn)品名稱

α-E-Catenin Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

844802

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	α-E-Catenin
Clone	1G5
Host Species	Mouse
Reactive Species	human, mouse, rat
Isotype	IgG1, κ
Format	purified
Size	100 μg
Concentration	n/a
Applications	Immunofluorescence Microscopy (IF), Western Blot (WB), IP
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Purified anti-α-E-Catenin. α-catenin associates with the cytoplasmic domain of a variety of plasma membrane spanning cadherins that mediate cell-cell adhesion. The association of catenins to cadherins produces a complex that is linked to the actin filament network, which seems to be of primary importance for their cell-adhesion properties. Catenin can associate with both E- and N-cadherins. It was originally thought to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and α-catenin was shown not to bind to F-actin when assembled in the complex suggesting a more complex, dynamic linkage between actin and these adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments.
Immunogen	Recombinant human MBP-alpha catenin fusion protein.
Other Names	Catenin (Cadherin-Associated Protein), Alpha 1, 102kD, Alpha-1-Catenin, Alpha E-Catenin , Cadherin-Associated Protein,102 kD, CAP102, CTNNA1
Gene, Accession #	Gene ID: 1495
Catalog #	844802
Price
Order / More Info	α-E-Catenin Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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