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產(chǎn)品名稱

ABCA4 Antibody from BOSTER BIO

產(chǎn)品貨號

A01048

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ABCA4
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal Picoband? antibody for Retinal-specific ATP-binding cassette transporter(ABCA4) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. ABCA4 (ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, this gene is mapped to 1p21-p13. And this gene is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Additionally, it is showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human ABCA4 (1890-1927aa FLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQR), different from the related mouse sequence by eight amino acids.
Other Names	Retinal-specific ATP-binding cassette transporter;ATP-binding cassette sub-family A member 4;RIM ABC transporter;RIM protein;RmP;Stargardt disease protein;ABCA4;ABCR;
Gene, Accession #	ABCA4, UniProt: P78363
Catalog #	A01048
Price
Order / More Info	ABCA4 Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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