| 產(chǎn)品詳情 |
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| Product Name | A-317491 |
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| Description | A P2X3 and P2X2/3 receptor antagonist (Kis = 22-92 nM in a calcium influx assay); selective over other purinergic and neurotransmitter receptors, ion channels, and enzymes (IC50s = >10 μM); reduces thermal hyperalgesia induced by complete Freund's adjuvant in rats (ED50 = 30 μmol/kg, s.c.) and nociceptive responses to chemically-induced pain; chronic administration reduces early, but not late, phase pain in a mouse model of bone cancer; does not readily cross the blood-brain barrier and reduces pain responses when applied topically, |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | A 317491 P2X3 P2X2/3 purinoceptor cancer |
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| Gene, Accession, CAS # | CAS: 475205-49-3 |
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| Catalog # | 19256-5 |
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| Price | |
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| Order / More Info | A-317491 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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