| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | A-443654 |
| Description | A pan Akt inhibitor (Ki = 160 pmol/L for all three isoforms) that interferes with mitotic progression and bipolar spindle formation; slows the progression of Akt-dependent tumors in vivo; concomitantly increases Akt Thr308 and Ser473 phosphorylation via a rapid feedback reaction |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Akt1 Akt2 Akt3 proteins kinases B PKB cancers cells proliferation inhibitors biochemicals signals tranductions inhibits inhibitions Akt-1 Akt-2 Akt-3 Akts 1 2 3 PK A443654 A 443654 pan isoforms PKBα PKBβ PKBγ α β γ modulates metabolism survivals angiogenesis mitotic progressions bipolar spindles formations induces G2/M G2 M accumulations defects centrosomes separations monopolar arrays disorganized Akt-dependent dependent tumors in vivo mouses models phosphorylation Thr Thr308 308 Ser Ser473 473 humans lines mechanisms rapid feedback reactions |
| Gene, Accession, CAS # | CAS: 552325-16-3 |
| Catalog # | 16499-1 |
| Price | |
| Order / More Info | A-443654 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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