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產(chǎn)品名稱(chēng)

Angiotensin I Converting Enzyme (ACE1) Inhibitor Screening Kit from CREATIVE BIOMART

產(chǎn)品貨號(hào)

Kit-2408

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 assays

產(chǎn)品品牌

CREATIVE BIOMART

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Angiotensin I Converting Enzyme (ACE1) Inhibitor Screening Kit
Description	Angiotensin I converting enzyme (ACE1, EC: 3.4.15.1), a dipeptidyl carboxypeptidase, is part of the renin-angiotensin system (RAS) that controls regulation of blood pressure by cleaving the C-terminal dipeptides of angiotensin I and bradykinin. It is found on the luminal surface of vascular endothelial cells, especially in pulmonary tissues. In addition, elevated levels of ACE1 are found in sarcoidosis, leprosy, hyperthyroidism, acute hepatitis, primary biliary cirrhosis, diabetes mellitus, multiple myeloma, osteoarthritis, amyloidosis, Gaucher disease, pneumoconiosis, histoplasmosis and miliary tuberculosis. ACE1 Inhibitor Screening Kit can be used to screen for potent inhibitors of ACE1 activity to regulate hypertension. It utilizes the ability of an active ACE1 to cleave a synthetic o-aminobenzoyl peptide (Abz-based peptide substrate to release a free fluorophore). The released Abz can be easily quantified using a fluorescence microplate reader. In the presence of an ACE1 specific inhibitor, the enzyme loses its peptidase activity which results in decrease of fluorescence intensity. This assay kit is simple and can be used to identify and characterize ACE1 inhibitors in a high-throughput format.
Size	100 assays
Concentration	n/a
Applications	Screening/studying/characterizing inhibitors of ACE1
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	Kit-2408
Price
Order / More Info	Angiotensin I Converting Enzyme (ACE1) Inhibitor Screening Kit from CREATIVE BIOMART
Product Specific References	n/a
產(chǎn)品資料

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