| 產品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | ASGPR/CD301 |
|---|
| Clone | 121A5.01 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100μg/50μg |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, FACS surface, WB, antigen capture endocytosis |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) / CD301 is a Ca(2+)-dependent type II transmembrane lectin. Immunoprecipitation from DCs using anti-DC-ASGPR mAb yields a major 40-kDa protein. ASGPR mRNA is observed predominantly in immune tissues (DCs and granulocytes), but not in T, B, or NK cells, or monocytes. ASGPR species are restricted to the CD14-derived DCs obtained from CD34(+) progenitors, while absent from the CD1a-derived subset. Accordingly, both monocyte-derived DCs and tonsillar interstitial-type DCs express ASGPR protein, while Langerhans-type cells do not. ASGPR is a feature of immaturity, as expression is lost upon CD40L activation. In agreement with the presence of tyrosine-based and dileucine motifs in the intracytoplasmic domain, mAb against DC-ASGPR is rapidly internalized by DCs at 37 degrees C. Finally, intracellular ASGPR is localized in early endosomes, suggesting that the receptor recycles to the cell surface following internalization of ligand. ASGPR/HML is a feature of immature DCs and a subtype of macrophages, and likely important for the specialized antigen-capture function of DCs.(Valladeau J et al, 2001 J. Immunol.,167: 5767) |
|---|
| Immunogen | n/a |
|---|
| Other Names | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0011 |
|---|
| Price | |
|---|
| Order / More Info | ASGPR/CD301 Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 產品資料 |
|
国内自拍激情视频,日韩欧美国产三级,亚洲人妻色色
|
A黄片,国产freexxxx性播放,艹艹艹逼
|
亚洲一区二区激情四射,一级片一级,波多野结衣视频在线观看
|
又大又紧18p粉嫩少妇,欧美激情乱人伦,淫淫色综合
|
欧美日韩肏屄视频,黄色视频日本,黃色一级一片免费播放
|
人人人人摸,男人午夜小视频,国产精品国产自产拍高清AV
|
韩漫歪歪,91女警花高潮国产,99久久精品国产国产毛片
|
久久久999黄色,在教室伦流澡到高潮h女女视,日本韩国欧美18
|
日韩亚洲美洲欧洲二三区在线看,欧美精品久久久久久,麻豆成人AV一二三区在线播放
|
免费播放片色情A片,日日夜夜精品视频免费,北条麻妃91视频
欧美草壁视频,欧美高潮被爽到呻吟,男女尻屄视频
|
|